Saturday, August 9, 2014

Amino Acids, Peptides, and Proteins ppt


They are important primary metabolites
Many are pharmacologically active compounds
antibiotics
antitumor
allergens
anti-inflammatory agents
Important components in the discussions of drugs (distribution, action, elimination of drugs)
Closely associated with genetic makeup
 
 
Histamine a decarboxylated derivative of histidine plays an important role in mediating the body's response to allergic reactions.
L-DOPA, which is a derivative of tyrosine, has been used to treat Parkinson's disease.
Thyroxine, which is an iodinated ether of tyrosine, is a hormone that acts on the thyroid gland to stimulate the rate of metabolism.
 
Amino acids: contain a basic amino group and an acidic carboxyl group
Peptides: are joined as amides between the -NH2 of one amino acid and the –CO2H to the next amino acid (< 50 units )
Protein: large chains that have structural or catalytic functions in biology
 


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