Heterocyclic compounds are organic compounds that contain a ring structure containing atoms in addition to carbon, such as sulfur, oxygen or nitrogen, as the heteroatom.
The ring may be aromatic or non-aromatic.
Most naturally occurring heterocyclic compounds and the medicinally important ones contain N, O, S or their combinations
are electronegative
Polar centers
Sites for hydrogen bonding
Render organic molecules reactive (mainly by making them nucleophiles or bases)
These properties enable them to be biologically active
Two thirds of all organic compounds are aromatic heterocyclic.
Most pharmaceuticals are heterocyclic.
Click HERE to read the complete lecture note on Hetrocyclic compunds
No comments:
Post a Comment